She reigned as the undisputed female welterweight boxing champion from 2014 to 2020, and is the first woman in any weight class to hold the WBA, WBC, IBF and WBO titles simultaneously.

In November 2007, Brækhus signed a pro contract with German promoter Wilfried Sauerland, who announced his intention of making her the first Norwegian female World Champion.

[12] Brækhus successfully defended her titles on later that year on 30 May against Amy Yuratovac in Helsinki, Finland,[13] and on 12 September 2009, against Lucia Morelli in Herning, Denmark.

On 14 September 2014, after defeating Croatian Ivana Habazin, Brækhus became the first Norwegian and the first woman to hold all major world championship belts in her weight division (welterweight) in boxing history.

[22][23] Brækhus claimed the vacant interim WBC female super-welterweight title with a unanimous decision win over Maricela Cornejo in Las Vegas on 10 August 2024.