[5] Rodríguez made his professional debut on 26 November 2010, defeating Christian Kamara by fourth-round technical knockout (TKO) in Las Palmas.

[14] After stopping an undefeated Davide Doria in five rounds in Las Palmas,[15] he made his U.S. debut on 27 February 2016, defeating Edgar Riovalle by unanimous decision at the Honda Center in Anaheim, California.

[16] On 13 May he defended his WBC Latino title against Carlos Saul Chumbita in Argentina, scoring two knockdowns in the first round before securing a TKO in the second to retain his belt.

[17] On 2 December 2016 he defeated Frenchman Ahmed El Mousaoui by split decision in Las Palmas for the vacant European welterweight title.

[20][21] After the loss he returned home to the Canary Islands to help with the family business in Jinámar, citing a lack of funds to continue boxing for the time being.