An anime television series adaptation produced by Liden Films aired from January 10 to March 21, 2021.

In contrast to the main series, which is set in a generally healthy human body, Cells at Work!

The story follows the anthropomorphic cells struggling to maintain the body against threats such as smoking, excessive alcohol consumption, and sexually transmitted infections.

Yugo Kanno is composing the music, Eiji Akibo is designing the characters for animation, and Liden Films is producing the series.

[23] Aniplex of America licensed the series and streamed it on Funimation starting on January 7, 2021, two days before the Japanese broadcast.

with Yamasaki Seiya (Kyūso Nekokami)", while the ending theme is "Ue o Mukaite Hakobō with Sekkekkyū/Hakkekkyū", both performed by Polysics.