The company focuses on creating military simulation games such as Operation Flashpoint: Cold War Crisis and the Arma series.

Following Operation Flashpoint was a series of downturns, such as porting the game to Xbox, which led to financial losses and the development of a sequel later abandoned by the publisher Codemasters.

Following Codemasters' decision of not supporting the studio, Bohemia Interactive decided to develop a spiritual successor to Cold War Crisis titled Arma: Armed Assault.

The same year saw the arrest of two employees of Bohemia, who were charged with espionage by Greece and jailed for 129 days, forcing the team to rename Arma 3's setting to a fictional one.

Bohemia Interactive founder Marek Španěl aspired to become a game developer in the 1980s, after his brother was convinced to buy a TI-99/4A computer.

Španěl first worked as a salesman for a game distribution company and made a 3D hovercraft simulator Gravon: Real Virtuality for Atari Falcon in 1995, which sold 400 copies only.

[5] He, along with his brother, Ondřej Španěl, and business partner Slavomír Pavlíček, decided to develop a game in 1997, using the money given by his former employers.

[6][7] The team initially wanted to develop a shooter named Rio Grande, which was described by Španěl as "a 3D clone of River Raid".

Despite these development issues, Poseidon was successfully released in June 2001 under the official title Operation Flashpoint: Cold War Crisis by Codemasters to critical acclaim.

[8] It was shipped without any game-breaking bugs, and it became an international success, selling more than 500,000 copies in its first three months of release, as well as reaching a top position in retail sales chart across the world including US, UK, Germany and Australia.

[9] Bohemia Interactive won Best Debut at the Game Developers Choice Awards, defeating strong opponents including Remedy Entertainment (Max Payne).

[6] Following the release of Operation Flashpoint: Cold War Crisis, the team intended to continue updating the game with post-release content, develop a port for the Xbox console, and create a sequel.

[13] In 2020 THQ Nordic acquired the entire team of Bohemia Interactive Bratislava which ceased to exist and all people joined newly created Nine Rocks Games.

[14][15] Additionally, in late 2020 30 people from Bohemia Interactive Brno were acquired by THQ Nordic and they joined newly created Ashborne Games studio.

[6] In the early 2000s, the US Army began using a mod of the game Operation Flashpoint: Cold War Crisis, named DARWARS Ambush!, to train soldiers.

In financial distress, Bohemia capitalized on its use and made a small sum of money, saving the company from falling into immediate bankruptcy.

But it is not right to promote this game as the ‘official sequel to the multi-award-winning Operation Flashpoint: Cold War Crisis or the ‘return' of Bohemia Interactive's ‘genre-defining military conflict simulator.'

[6] During this period, Codemasters announced Operation Flashpoint: Dragon Rising, a game falling into competition with Bohemia's own Arma titles, as it was marketed as the true successor to Cold War Crisis.

[17] Španěl was not happy with how Dragon Rising was being marketed as a return to the Operation Flashpoint series despite being created without the involvement of Bohemia.

[18] The team became anxious, but found relief after viewing gameplay footage Dragon Rising', which they considered to be subpar and "[did] not come even close to what they promised".

[19] Following the release of Operation Arrowhead, the company started development of a new Arma game, this time set in the future.

While the main goal is to transit the mod into an entirely new game, the team also intended to add more content such as base-building and improved crafting.

[44][45] Bohemia Interactive also had a close relationship with International Committee of the Red Cross, in which they partnered together for a special award named Health Care in Danger Special Award at the Make Arma Not War competition, and Bohemia also promised to follow some of Red Cross' suggestions on how video games should handle war crimes.