The club was founded on 14 January 2003 and played its home games at the Manuel Calle Lombana stadium, which has a capacity of 15,000 seats.

The club was founded on 14 January 2002 and abolished the rise in the first season immediately on from the second division to the Categoría Primera A.

In the end of this season, they reached the fourth place and thus even the qualification of the Cuadrangulares, Colombian Championship Playoffs.

The club was standing with Atletico Bucaramanga and Deportivo Tuluá level on points at the last place in the table, but increased due to the poor goal difference again in the second division.

In May 2011, Centauros moved from Villavicencio to Popayán considering its huge debts, the refusal of financial support from successive local authorities that deemed it a feeder club for Deportes Quindío, and the support expressed from the Cauca Department Governorate for a football club in the department's capital city, thus becoming Universitario Popayán.