In June 2003, during China's paramount leader Hu Jintao's visit to Kazakhstan, agreements to expedite the appraisal of the project were signed.

[5] In June 2007, during his visit to China, Turkmen President Gurbanguly Berdimuhamedow signed an accord to speed up implementation of the Turkmen-Chinese gas pipeline project.

[8] On 8 November 2007, Kazakhstan's oil company KazMunayGas signed an agreement with the China National Petroleum Corporation on principles of future work on the pipeline.

[18] The Kazakh section of the pipeline was inaugurated on 12 December 2009 during Chinese leader Hu Jintao's visit to Kazakhstan.

"[25] S&P Global reported in December 2023, "PetroChina expects to resume the construction of Line D of the Central Asia – China Gas Pipeline (CAGP) in 2024..." and "...the contract was still under final negotiations.

The main disagreement remaining was over prices and the delay in finalizing the upstream gas supply contract was the main reason for the suspension of Line D's construction..."[26] According to CNPC, the inflow of Turkmen gas helps China in meeting its energy demands and stabilizes the country's overall consumption structure.

It was expected that the pipeline's deliveries boost the natural gas proportion of energy consumption of China by an estimated 2%, which reduces the overall smoke, dust and carbon dioxide emissions.

[27] For Turkmenistan, the project helps the country diversify its energy exports by delivering gas eastward as opposed to its previous deliveries to Russia and Iran.

While Kazakhstan and Uzbekistan are also considering selling their gas to China, Chinese government already made new moves to penetrate deeper into Central Asian energy sector by lending $3 billion to Turkmenistan to develop the South Iolotan field in 2009 and $10 billion to Kazakhstan to pay for future oil supplies.

[30] The pipeline project also includes the desulfurization plant at Samand-Depe to remove high sulfur content of natural gas.

[31] A fourth pipeline (Line D), 966 kilometres (600 mi) in length to connect Galkynysh to western China via Kyrgyzstan and Tajikistan, is under construction.