Originally named Central High School, it was the result of the merger of Academy High School and Technical Memorial High School after the conclusion of the 1992–1993 academic year when Academy closed.

The attendance was roughly 1,000 students, and offered 21 Career and Technical courses.

In 2017, Central Tech High School was renamed Erie High School (Pennsylvania) when the School District of the City of Erie consolidated all of its high schools—with the exception of Northwest Pennsylvania Collegiate Academy.

[2] When occupancy of newly built Academy High School was delayed in the fall of 1919, those students shared facilities with Central through June 1920.

The Class of 2014 is the school's most successful, having won a share of the Region AAA title in District 10, during the 2013 season.