Centre Calgary was a provincial electoral district in Calgary, Alberta, Canada, mandated to return a single member to the Legislative Assembly of Alberta using the first past the post method of voting from 1913 to 1921.

Conservative candidate Thomas Tweedie won the Centre Calgary's first election held in 1913.

The Conservatives had a wave of support due to the unpopularity of the Sifton government in power at the time.

Thomas Tweedie was defeated in a stunning upset by the Calgary Labor temple member Alex Ross.

Ross held the electoral district until it was abolished in 1921, as Calgary was reformed into a five-member seat.