In collaboration with the British Medical Journal, Carl Heneghan and team found no evidence that Tamiflu helped to reduce complications of influenza.

[7][8] This has become a controversial topic, as the United Kingdom government spend £473 million (as of 2014[update]) on the purchase of Tamiflu, despite the systematic review[9] claiming to find no evidence for the effectiveness of it.

[13] A linked article published in the BMJ reported a "striking lack of evidence" to back up claims for popular sports brands.

[14] Systematic review and individual patient data meta analysis research[15] in the centre has shown that, even with little training, people on oral anticoagulation (warfarin) can successfully self-monitor, and even self-manage their disease in the community.

[17] In 2014, Carl Heneghan along with Alison Ward became directors of a World Health Organization Collaborating Centre for self-care in non-communicable disease.

[18] The centre is one of the co-founders of the AllTrials campaign, which has been influential in ensuring that the results of all clinical trials are registered and reported in full.