Centreville is a town in Amite and Wilkinson counties, Mississippi, United States.

It is part of the McComb, Mississippi micropolitan statistical area.

[4] According to the United States Census Bureau, the town has a total area of 2.3 square miles (6.0 km2), all land.

According to the 2020 United States census, there were 1,258 people, 724 households, and 374 families residing in the town; the racial and ethnic composition of the town was 71.3% Black and African American, 25.6% non-Hispanic white, 0.24% Native American, 0.08% Asian, 2.31% multiracial or of another race/ethnicity, and 0.48% Hispanic or Latino of any race in 2020.

[8] Private schools: Both Amite and Wilkinson counties are in the district of Southwest Mississippi Community College.