Working together with families, the Centro Ponceño de Autismo aims to identify the causes of autism and advance effective treatments.

Its location in the Ponce Historic Zone on Calle Sol at N 18.01284 W 66.61923 (18°00'46.224" North, 66°37'9.228" West), in barrio Segundo, a few blocks just northwest of Plaza Las Delicias and the Terminal de Carros Publicos Carlos Garay makes it easily accessible to public transportation.

[23] In 2007, the Autonomous Municipality of Ponce made public its intention to formally initiate the first phase of the development of the Autism Center, under the supervision of its First Lady, Mrs. Nancy Colón de Zayas.

Mayor Zayas Seijo, while serving in the House of Representatives, in collaboration with former senator Ortiz Dalliot, secured 1.7 million dollars from local government funds for the development of this project in Ponce.

[32] The center has trained over 500 primary care physicians in Puerto Rico on clinical issues related to the treatment of autism.

The municipality covers expenses such as utilities, security, and physical plant maintenance, in addition to absorbing the cost of space rental.

[40] In 2010, the Government of Puerto Rico approved Resolución Conjunta 487 assigning $520,000 to the Municipality of Ponce for operating the center.

The clinical services team at the Center consists of psychologists, psychiatrists, geneticists, and social workers with specialized training in Autism Spectrum Disorders.

The center has in its staff five specialists that include one of the few pediatric neuropsychologists in Puerto Rico, a speech pathologist who specializes in autism and an occupational therapist.