Centro Santa Fe[a] is a large 210,400-square-metre (2,264,727 sq ft)[1] enclosed shopping mall in the Santa Fe area in the far west side of Mexico City.

[2] Centro Santa Fe is the largest shopping center in Mexico.

Within the Centro Santa Fe, two floors above the Sears wing are separately branded as Vía Santa Fe,[5] containing mid-luxury clothing retailers (e.g. Salvatore Ferragamo, La Martina, Dolce & Gabbana), a Cinemex "Platinum" luxury multi-cinema, Casa Palacio (home store run by El Palacio de Hierro), and Mexico's first Apple Store.

Anchors in the main mall are El Palacio de Hierro, Liverpool, Sanborns and Sears department stores, and a Chedraui Select hypermarket.

As of 2012 the center as a whole had about 1,500,000 visitors per month or 20 million per year.