Cerignola is situated in south of the province of Foggia, and spans from the Salt Marshes of Margherita di Savoia to the borders with Basilicata region.

[3] Cerignola is the second biggest town of Capitanata for its number of inhabitants as well as for being the largest agriculture centre in its province.

Cerignola occupies the site of Furfane, a station on the ancient Roman Via Traiana between Canusium and Herdoniae.

The wine is a blend of at least 55% Uva di Troia, 15-30% Negroamaro, and up to 15% of an assortment of Sangiovese, Barbera, Montepulciano, Malbec and Trebbiano.

The local football team is the Audace Cerignola, and its home ground is the Domenico Monterisi Stadium.