Châtelus-le-Marcheix (French pronunciation: [ʃatly lə maʁʃɛ]; Occitan: Chasteluç lo Marchès) is a commune in the Creuse department in the Nouvelle-Aquitaine region in central France.

A village of farming, forestry, lakes and streams situated some 22 miles (35 km) southwest of Guéret by the banks of the Taurion river and at the junction of the D5, D8 and the D48 roads.

The village lies on the pilgrimage path of the Way of St. James.

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