The Chéticamp River is a river on Cape Breton Island, Nova Scotia, located at the western entrance to Cape Breton Highlands National Park which includes Acadian Trail.

According to estimates by the Province of Nova Scotia, there are 2,650 people resident within the Chéticamp watershed in 2011.

Some of the outflow of the lake has been diverted for the Wreck Cove Hydroelectric System project.

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