[2]: 20–21 It includes the 1890-built Hotel Chadron, which is separately listed on the National Register.

[2] Chadron was founded as a city in 1884, and grew rapidly as arrival of the Fremont, Elkhorn & Missouri Valley Railroad (FE & MV, a predecessor of the Chicago and North Western Railroad) was expected soon.

It hit 3,000 population in two years and 5,500 by 1893, before dropping due to droughts and the Panic of 1893.

These are significant as they "are the buildings that housed the businesses that enabled Chadron to establish itself as, and then to service the surrounding region as, a prominent trade center.

This article about a property in Nebraska on the National Register of Historic Places is a stub.