Chairman Blake House is a historic private home located at Davidson, Mecklenburg County, North Carolina.

It was built about 1860, and is a 1+1⁄2-story, five-bay, double pile Greek Revival style frame dwelling with a one-story rear ell.

It has steep side gable roof, four brick interior chimneys, and weatherboard sheathing.

It was the home of Professor John Rennie Blake (1825–1900), who is believed to have occupied the house throughout his tenure at Davidson College, 1861–1885.

This article about a property in Mecklenburg County, North Carolina on the National Register of Historic Places is a stub.