[3] According to Pouqueville the name "Chalandritsa" stems from "Χαλασμένη Τριταία" ("broken Tritaia"), referring to bad climate.

Triantafyllou[4] suggests that it comes either from the nearby town Chalampreza that was abandoned in the early 19th century, or from the Byzantine word Chalandra.

Chalandritsa was the last barony remaining in Frankish hands, and its fall to the Despotate of the Morea in 1429 also signalled the end of the Principality of Achaea.

In July 1943, during World War II, the occupying Italian army fired on Chalandritsa in retaliation for a partisan attack.

During the Greek Civil War, in 1948, Chalandritsa was the scene of fierce fighting between government and rebel forces.