Chanute High School offers a variety of courses, including concurrent classes through Neosho County Community College.

With the construction of the new high school in 2008, a new trade building was completed.

Foreign languages courses include Spanish I-IV.

Student groups and activities at Chanute High School include Blue Comet Bands, Chess Club, Blue Comet Debate League, Blue Comet Forensics League, drama, Dungeons & Dragons, Family, Career and Community Leaders of America, Fellowship of Christian Athletes, Foreign Language Club, Future Business Leaders of America, HOSA (organization), history club, Kansas Future Educators of America, Leadership club, Model United Nations, National Honor Society, SkillsUSA, Student Government, Talent Search, Teen Age Republicans, Upward Bound, and vocal/choral music.

The school's athletic teams, known as the Chanute Blue Comets, compete in Kansas State High School Activities Association size classification 4A.