(alternate spelling: Messolonghi) (Greek: Χαρίλαος Τρικούπης Μεσολογγίου K.A.E.)

It is a part of the multi-sports club Gymnastikos Syllogos Charilaos Trikoupis Messolonghi (Greek: Γυμναστικός Σύλλογος Χαρίλαος Τρικούπης Μεσολογγίου), which is abbreviated as G.S.

The club is named after Charilaos Trikoupis, who served seven terms as the Prime Minister of Greece, in the 19th century.

From 1959 to 1971, the club organized local basketball tournaments and competed in friendly games.

When the club temporarily moved to Agrinio, Greece, for the 2020–21 season, it played its home games at the 1,500 seat Michalis Kousis Agrinio Indoor Hall, which is named in honor of the late Greek marathon runner Michalis Kousis.

Note: Flags indicate national team eligibility at FIBA-sanctioned events.