Charles-Eusèbe Casgrain (December 28, 1800 – February 29, 1848) was a lawyer and political figure in Lower Canada.

In the same year, he married Eliza Anne, the daughter of James Baby who was a judge and political figure in Upper Canada.

He was elected to the Legislative Assembly of Lower Canada for Kamouraska in 1830; he did not support the Ninety-Two Resolutions.

Casgrain served on the Special Council which administered the province after the Lower Canada Rebellion.

His daughter Suzanne married Charles Alphonse Pantaléon Pelletier who went on to serve in the Senate of Canada and to become Lieutenant-Governor of Quebec.