Charles's crippled (by a fall when aged eight) epileptic elder brother, Humphry, died of a consumption unmarried in 1752.
A small part of her family correspondence is preserved in the Special Collections Department of the University of Birmingham.
[7] In 1769 Ambler and Thoroton were put forward by Lord Granby for the Bramber constituency and though defeated they were returned on petition.
He did not stand at the following election but in 1775 he was returned for Newtown and provided steady support to North acquiring the name "Tully Ambler, an ironical title which he does not owe to his abilities".
[1] He succeeded his wife's kin Sir William Blackstone as solicitor-general to Queen Charlotte 1771–1782 and then her attorney-general 1782–1794 In 1790 he published Reports on Cases in Chancery, 1737–83.