Fane interrupted his duties as member for Tavistock when he was appointed Minister Plenipotentiary (British Resident) to the Tuscan court in March 1734, with an annual salary of 1,300 pounds.
Here's Mann in a letter to Walpole of 7 September 1745: He joined White's Young Club (a sub-set of the original) in its foundation year 1743.
On 7 June 1749 Fane married at St Benet Paul's Wharf, Susanna, Lady Juxon (1706–10 April 1792).
She was the youngest daughter of John Marriott, Registrar of the Court of Chancery, of Stuston Hall, near Diss in Suffolk, and of Sonning in Berkshire.
Fane's leasehold dwelling-house, still extant, on the north side of Curzon Street in London, was bought from Elizabeth Shepherd in 1753.
He negotiated with the ground landlord, Nathaniel Curzon, for a wider site and added the two-bow fronted wings.
In 1984 the Saudi Arabian government bought it, by then known as Crewe House, for its embassy, paying 37 million pounds.