Charles Henry Keyes (6 September 1858 – 16 January 1925), was an American educator.

In 1911, Keyes wrote a well-received study on the progress of education in a New England school district.

[1] Keyes was already successful at Throop and Columbia University Teachers' College when Lucy Skidmore Scribner asked him to become Skidmore's first president.

Keyes helped define the school as a liberal arts college with a successful nursing program.

[2] He is the subject of a biography by Maud Keyes Decker (ISBN 143255882X).