Charles Louis, Count of Nassau-Saarbrücken (6 January 1665 – 6 December 1723) was the son of Count Gustav Adolf of Nassau-Saarbrücken and Countess Clara Eleanor of Hohenlohe-Neuenstein.

He was born in Saarbrücken, but was brought up by Wolfgang Julius of Hohenlohe-Neuenstein the brother of his mother, and continued his studies in Tübingen and Paris.

In the Great Turkish War, he served as an officer in the army of Emperor Leopold I.

In Warndt he expanded the glass works, which had been established already under Louis II by settling Huguenot refugees.

As both his sons died in infancy, the government of Nassau-Saarbrücken was inherited by father-in-law Frederick Louis of Nassau-Ottweiler.