Charles W. Crawford (July 21, 1888 – September 15, 1957) was an American chemist who served as Commissioner of Food and Drugs from 1951 to 1954.

He graduated Oklahoma A&M University with a BA degree in chemistry in 1909.

He later received a master's degree in 1915.

He quickly became the FDA's principal representative during the drafting of the 1938 Food, Drug, and Cosmetic Act.

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