One result of the visit was the production on his return of Whittingham's French Classics by the Chiswick Press; a series of Pocket Novels was also issued under his supervision.
In 1824 his uncle took him into partnership, then dissolved in 1828, and the younger Whittingham started a printing office at 21 Took's Court, Chancery Lane.
[1] In 1854 Whittingham lost his wife and his friend Pickering, and in 1860 took his manager John Wilkins (died 1869), into partnership, and retired from active work.
[1] The two Whittinghams printed Knickerbocker's New York (1824), Pierce Egan's Life of an Actor (1825), Samuel Weller Singer's Shakespeare in ten volumes (1825), and other books.
[1] The years 1843 and 1844 marked the introduction of the antiquarian style of book production, for which Whittingham and Henry Cole were mainly responsible.
In 1843 Whittingham had the Caslon Foundry revive an old face font of great primer cut in 1720, with an Eton prize Juvenal for Pickering and the Diary of Lady Willoughby for Longman printed in it.
They had five children—William, Charlotte, Elizabeth Eleanor, Jane, and Charles John—all of whom were connected with the Chiswick Press, the daughters involving themselves in the literary and artistic departments.
Charlotte and Elizabeth trained as artists, and worked on borders, monograms, head and tail pieces, and other embellishments.