Reverend Charles William Nassau D.D., (April 12, 1804 – August 6, 1878) was a Presbyterian minister and the fourth president of Lafayette College serving from 1849 to 1850.

From 1829 to 1833 he taught at an all-boys school in Philadelphia before overcoming his health issues and practicing as a pastor, again in Norristown, from 1832 to 1833.

[1] Starting in 1836, Nassau became a professor of Latin and Greek at Marion College, in Hannibal, Missouri.

Despite Nassau's education, he was unable to turn the financial situation around, and left the position in September, 1850 when debtors began to take legal action against the school.

[4] After the presidency at Lafayette, Nassau became head of the Young Ladies' Seminary in Lawrenceville, New Jersey.