Known as one of the pioneers of double bass drumming and credited for popularizing the blast beat technique, he is Anthrax's main composer and has released eleven studio albums with the band.

Along with his musician duties, Benante is also a graphic artist and has created many of Anthrax's album covers and T-shirt designs.

"[9] On July 14, 2022, it was announced that Benante had joined the reunited Pantera by filling in for original drummer, and his close friend, Vinnie Paul.

[13][14] Benante later missed the band's UK and European tour in order to take care of "personal stuff" according to Scott Ian.

[18] Benante uses and endorses Tama drums and hardware, Paiste cymbals, Vic Firth sticks,[19] Evans Drumheads,[20] and Roland electronics.