Charlie Chan's Murder Cruise is a 1940 murder mystery film starring Sidney Toler in his fifth of many performances as Charlie Chan.

It is based on the Earl Derr Biggers 1930 novel Charlie Chan Carries On.

The famed detective seeks to unmask a killer on a voyage across the Pacific Ocean.

Charlie Chan's Murder Cruise is the second film adaptation of Earl Derr Biggers' novel Charlie Chan Carries On.

The first version, with Chan played by Warner Oland, is now lost.