Charlotte's Web (cannabis)
Charlotte's Web is a brand of high-cannabidiol (CBD), low-tetrahydrocannabinol (THC) products derived from industrial hemp and marketed as dietary supplements and cosmetics under federal law of the United States.
"[6] Her parents and physicians say she experienced a reduction of her epileptic seizures brought on by Dravet syndrome after her first dose of medical marijuana at five years of age.
[7][8] While initially anecdotal reports sparked interest in treatment with cannabinoids,[9] there was not enough evidence to draw conclusions with certainty about their safety or efficacy.
[10] A 2014 review by the American Academy of Neurology similarly concluded that "data are insufficient to support or refute the efficacy of cannabinoids for reducing seizure frequency.
"[19] The Cochrane review suggests cannabinoids be reserved for people with symptoms that are not controllable by other means, who have been evaluated by EEG-video monitoring to confirm diagnosis, and are not eligible for better-established treatments such as surgery and neurostimulation.
[21] A third review found that no reliable conclusions about the effect of cannabis on epilepsy could be drawn due to the poor quality of available data, but further research may be warranted because of the good safety profile observed in small clinical trials.
[29][30] Since then, Florida legislators have passed a bill with bipartisan support legalizing the use of Charlotte's Web,[31] and Governor Rick Scott signed the "Compassionate Medical Cannabis Act of 2014" (SB 1030)[32][33] into law on June 6, 2014.
[34][35] The law specifies the number of distribution centers, which types of nurseries can grow the plants, requires various other controls,[36] and provides funding for research.
[32] On October 31, 2017, the FDA sent warning letters to four CBD marketers, including Stanley Brothers Social Enterprises, LLC (d/b/a CW Hemp), the producer of Charlotte's Web.
[14] Charlotte's story has been featured on two CNN documentaries,[48][16] The Doctors TV show,[49] 60 Minutes Australia,[50] and Dateline NBC,[51] among many other sources.
[16] The extract received more publicity on October 6, 2014, when The Doctors TV show again featured a story about usage of Charlotte's Web.
[58] On the October 17, 2014, episode of the ABC TV series The View, Paige Figi and Joel Stanley were interviewed by Whoopi Goldberg and Nicolle Wallace.
Amy Brooks-Kayal, vice president of the American Epilepsy Society, stated that epileptic seizures may come and go without any obvious explanation, and that Charlotte's web could cause developmental harm.
She recommended that parents relocate so that their affected children could have access to one of the nation's top pediatric epilepsy centers rather than move to Colorado.
[68] In November 2013, Josh Stanley said that Charlotte's web was 0.5% THC and 17% CBD,[12] and that it "is as legal as other hemp products already sold in stores across Utah, including other oils, clothing, and hand creams, but is illegal, federally, to take across state lines.
