The Independence currently play their home games at American Legion Memorial Stadium in the Elizabeth neighborhood of Charlotte, North Carolina.

[6] After recording their best season in 2021, finishing second in the Atlantic Division, the club decided to drop down to the third tier USL League One for 2022, with the goal of better serving its youth players, as well as the fact that a new expansion franchise in the city Charlotte FC was joining Major League Soccer that season, with whom several Independence players had signed.

In 2016, the club began working with Mecklenburg County on a refurbishment of American Legion Memorial Stadium.

Previously, the Independence played matches in the greater Charlotte region at the Sportsplex in Matthews in Matthews, North Carolina, Ramblewood Soccer Complex, the University of North Carolina at Charlotte's Transamerica Field and Winthrop University's Eagle Field.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

The Ultras and Reserves help create the supporters section atmosphere with Blue Furia, an independent predominantly Hispanic supporters group, and La Femme Footie, a group that works to promote women's soccer and women's involvement in the sport.

The Independence competed for the Southern Derby against their rival, the Charleston Battery while Charlotte was in USL Championship.

The club's original independent supporters' group, "Jack's Militia", was founded in 2012 to promote soccer in Charlotte.

Serving North Carolina communities such as Belmont, Cabarrus, Cornelius, Davidson, Denver, Gastonia, Huntersville, Matthews, Mooresville, North Meck, South Charlotte, Statesville, and Steele Creek, as well as Fort Mill, Rock Hill and York County in South Carolina.