[3] The founding group incorporated under the name Charlotte Latin School with a 13-member board of trustees: Carol Belk, Patrick Calhoun, Tom Creasy, Jr., Alan Dickson, Cam Faison, Catherine Faison, Betsy Knight, Bob Knight, John Pender, Howard Pitt, John Stedman and Janet Thies.

[4] After receiving adequate response the trustees secured approximately 50 acres of land near the intersection of Providence Road and Highway 51 in suburban Charlotte.

[9] In October 1970 a standard review by the Internal Revenue Service granted the school tax exempt status after it printed its non-discrimination policy in the local newspaper.

[26][27] At the end of his 18-year tenure, Charlotte Latin opened the Inlustrate Orbem Building, a 50,000-square-foot facility housing upper school classrooms as well as the admissions, college counseling and development offices.

[31] During the 1976–1977 school year, Charlotte Latin was awarded a charter to the Cum Laude Society, an organization that honors scholastic achievement at secondary institutions.

[34] Charlotte Latin has been recognized with the Blue Ribbon School of Excellence Award from the United States Department of Education on three different occasions.

Charlotte Latin is one of fifty Malone Scholars schools in the country, which are selected by the Malone Family Foundation for their: "academic caliber; the quality of their staff; excellent accommodations for gifted and talented students; strong AP/IB and enrichment programs; attention to the individual student's needs, interests, and talents; financial strength and stability; a commitment to financial aid; and an economically, culturally, ethically, and socially diverse population.

"[37][38] In 2020, PolarisList ranked Charlotte Latin first in the Mecklenburg area for sending students to elite colleges after a study conducted over the four-year period from 2015 to 2018 that measured enrollment at Harvard, Princeton, and MIT.

Founded at the Massachusetts Institute of Technology, the Fab Lab focuses on using engineering and digital fabrication to solve real world problems through use of many different tools provided.

[42] Digital design programs in use in the CLS Fab Lab include Fusion360, Cameo Silhouette Studio, the Adobe suite, and CorelDRAW.

In March 2020, a student-led campaign supervised by Fab Lab director and Charlotte Latin teacher Tom Dubick raised in excess of $100,000 and utilized the school's facility to design and print 3D and injection molded face shields for medical professionals in need of PPE during the COVID-19 pandemic.

[68][64][69][70][71][72][73][74] Charlotte Latin has won a total of 165 state championships across 21 men's and women's sports programs since the inception of the NCISAA in 1973:[75]