She was born as daughter of Carl Caspar, Baron von Gaugreben (1716-1767) and Baroness Agnes Posse of Säby (b.1727).
Charlotte married Baron Otto Heinrich von Lieven (1726-1781), member of one of the oldest aristocratic families of German Baltic origin.
[1] She was in 1783 appointed by Grand Duke Paul with the task of educating his daughters and younger sons - Nicholas and Mikhail Pavlovich.
On 22 August 1826, she was granted the hereditary title of Princess in the Russian Empire by Nicholas I, Emperor of Russia.
[2] Alexander von Lieven: Der General Baron Otto Heinrich von Lieven und seine Gemahlin, die Staatsdame Charlotte geb.