Chascomús is an east central partido (administrative district) of the Province of Buenos Aires in Argentina.

Chascomús, like most of Buenos Aires province, has many beef cattle and dairy farms.

Agricultural produce from the area includes maize, wheat, barley, oats, soya beans, and sorghum, while apiculture also plays a role in the local economy.

The district also has a strong industrial sector, producing dairy products, textiles and agricultural machinery.

The tourist industry in Chascomús is mainly dominated by weekend tourism from Greater Buenos Aires.