Chavagnes-en-Paillers (French pronunciation: [ʃavaɲ ɑ̃ paje]) is a commune of the Vendée department in the Pays de la Loire region in western France.

Chavagnes en Paillers is known as one of the two villes saintes (holy towns) of the Vendée.

It is home to the mother-houses of two religious congregations: the Sons of Mary Immaculate and the Ursulines of Jesus, both founded by the Roman Catholic priest Louis-Marie Baudouin in about 1802 in the wake of the French Revolution (1789) and the War in the Vendée (mainly 1793-1796).

Still present also in Chavagnes is the seminary Baudouin founded for the training of boys and men destined for the priesthood.

The word Chavagnes is thought to come from the dog Latin cabanas, meaning cabins.