[1] Starting as a jack-of-all-trades and columnist for the Armenian daily Sourhandak, he published revolutionary literature and worked for the Dashnak newspapers Droschak and Razmig.

In 1911, he moved to Garin (Erzurum) to replace the assassinated columnist Yeghiché Topjian for the Dashnak newspaper Haratch and traveled to the regions of Moush and Sassoun with an armed escort led by Stepan Zorian.

[1] In November 1922, Chavarche Missakian was forced to exile in Sofia, where he married Dirouhie Azarian[2] (1891–1964), a teacher in Dörtyol in 1913 and later an accountant for the newspaper Djagadamard.

[7] The newspaper operated uninterrupted until the Occupation when Missakian, a committed socialist, voluntarily ceased its publication in opposition to Nazism and resumed it after the Liberation.

After World War II, as the USSR encouraged the immigration of diaspora Armenians to Soviet Armenia to compensate for wartime losses, Missakian tried to dissuade potential emigrants by warning them of likely disappointments, advising them to accept the "rose with thorns.