[6] She has an older brother, internet entrepreneur Jonah Peretti, co-founder of BuzzFeed and The Huffington Post.

[14] Peretti has written for The Village Voice, Details, Playgirl, Jest, and American Theatre Magazine, as well as online publications including The Huffington Post.

[16] From 2013 until 2019, Peretti was a series regular on NBC's detective/police comedy Brooklyn Nine-Nine, playing Gina Linetti, until she announced her departure from the show in October 2018.

While in New York, Peretti made short films with Variety SHAC, a comedy troupe she formed in 2004 with Andrea Rosen, Heather Lawless, and Shonali Bhowmik.

"[22] On April 21, 2020, Peretti released an EP titled Foam and Flotsam, a musical comedy concept album about coffee.

[23] She created the music in collaboration with Kool Kojak, and the songs feature guests Reggie Watts, Terry Crews, and Juliette Lewis.