The song had been streamed more than 12 million times prior to the single's release and has been called a "fan favourite".
"[2][5] During a live performance in November 2017, Lewis added "My friends thought this song was about drugs.
"[6] Lewis first performed "Chemicals" at a house in East London for the renowned UK Mahogany sessions.
[7] The video tracks the relationship of a young couple who are struggling with the concept of being together, and stars Brayden Dalmazzone and Lana Kington.
[8] In a review of the EP, Chelsea King from Forte Magazine said "While some of the tracks blur together, "Chemicals" is a song that stands out for its haunting nature.