Chemistry is the first collaborative studio album by American rapper Buckshot and record producer 9th Wonder.

It was released on June 21, 2005 through Duck Down Music as a part of the label's "Triple Threat Campaign", preceded by Sean Price's Monkey Barz and followed by Tek & Steele's Smif 'n' Wessun: Reloaded.

Recording sessions took place at Missie Ann Studios in Raleigh, North Carolina.

Production was handled entirely by 9th Wonder, with Buckshot and Drew "Dru-Ha" Friedman serving as executive producers.

It features guest appearances from Keisha Shontelle, Big Pooh, Joe Scudda, L.E.G.A.C.Y., Phonte, Sean Price and Starang Wondah.