The Chenagai airstrike took place on October 30, 2006, around 5:00 am local time in the Chenagai village of Bajaur Agency (today Bajaur District) of the Federally Administered Tribal Areas (FATA, today Khyber Pakhtunkhwa Province, KPK) on Pakistan's western border with Afghanistan.
Security and terrorism commentator Alexis Debat reported the target of the strike was Ayman al-Zawahiri, al-Qaeda's second-in-command.
Though Zawahiri was not among the dead and was killed in a July 2022 airstrike in Kabul, two to five senior al-Qaeda commanders were present or during or shortly before the attack including Matiur Rehman Ali Muhammad, mastermind of the 2006 transatlantic aircraft plot, and Faqir Mohammad, a close friend of Zawahiri and deputy leader of Tehrik-e Taliban Pakistan (TTP).
The leader of the madrassa, cleric Maulana Liaqat Ullah Hussain, was suspected to be sheltering al-Qaeda militants and was among the dead.
[6] On November 8, 2006, a suicide bomber killed 42 Pakistani soldiers and injured 20 others in Dargai, 85 miles north-west of Islamabad.