Cherokee is a city in Crawford County, Kansas, United States.

It was named from Cherokee County, where it was erroneously thought to be located.

[7] According to the United States Census Bureau, the city has a total area of 0.71 square miles (1.84 km2), all of it land.

[8] The 2020 United States census counted 590 people, 246 households, and 151 families in Cherokee.

There were 306 housing units at an average density of 427.4 per square mile (165.0/km2).

32.1% of households consisted of individuals and 14.2% had someone living alone who was 65 years of age or older.

[14] The percent of those with a bachelor's degree or higher was estimated to be 18.6% of the population.

There were 324 housing units at an average density of 456.3 per square mile (176.2/km2).

27.3% of all households were made up of individuals, and 10.8% had someone living alone who was 65 years of age or older.

There were 336 housing units at an average density of 489.7 per square mile (189.1/km2).

32.2% of all households were made up of individuals, and 16.6% had someone living alone who was 65 years of age or older.