Chesapeake is a village in Lawrence County, Ohio, United States.

It lies across the Ohio River from Huntington, West Virginia, at the mouth of Symmes Creek.

The Robert C. Byrd Bridge across the Ohio River connects Chesapeake to Huntington's downtown area.

Chesapeake is a part of the Huntington-Ashland, WV-KY-OH, Metropolitan Statistical Area (MSA).

There were 399 housing units at an average density of 848.9 per square mile (327.8/km2).

37.7% of all households were made up of individuals, and 17.9% had someone living alone who was 65 years of age or older.

There were 441 housing units at an average density of 798.0 per square mile (308.1/km2).

37.2% of all households were made up of individuals, and 17.0% had someone living alone who was 65 years of age or older.