The Uplands Meeting had been organized by Robert Wade, who arrived in the area in 1675, from earlier Quaker settlements in New Jersey.

[2] This group of Friends met in member's homes until about 1688 when a 24-foot (7.3 m) square meetinghouse was built on two acres.

The land was sold on October 4, 1688 by James[3] Brown for 1 shilling and sixpence "only for the use of the people of God, called Quakers.

The doors show bullet holes incurred from British foraging parties after the Battle of Brandywine in September, 1777.

No modern conveniences such as heat, plumbing or electricity have been added to the building, so it is considered to be in pristine condition.