Major tributaries in Florida include Holmes, Wright, Sandy, Pine Log, Seven Run and Bruce creeks.

[citation needed] Twenty-one Aquatic Snails and Freshwater Mussel species exist in the Choctawhatchee, with one of the former and two of the latter found only in this particular river.

[7] Trees found along the Choctawhatchee include southern pine, beech, magnolia, laurel oak, basswood, Florida maple and American holly.

[8] The Choctawhatchee has little industry along its banks; consequently it has rather clean water, except for excess turbidity, usually due to runoff from unpaved county roads.

The Choctawhatchee, Pea and Yellow Rivers Watershed Management District was instrumental in getting a grant to place gravel on many county roads, which reduced the average turbidity.

The Lincoln Freshet induced many of the townspeople to move to higher ground approximately a half-mile north, while the Hoover Flood swept away most of the remnants of Old Town Geneva.

Sam Story, also known as Timpoochee Kinnard, was chief of a band of Euchee (Yuchi) Indians in the early 19th century in present-day Walton County.

His parents were a Yuchi woman, whose name is not known, and Timothy Kinnard, a white man of Scottish descent, who had come to the area as a trader.

[citation needed] In 1814 Andrew Jackson built a stockade called the "Block House" at the confluence of the East and West forks of the Chocktawhatchee, near Newton.

During the American Civil War, the Confederate steamboat Bloomer was the object of an 1862 raid by 25 Union soldiers of the 91st New York State Volunteers, who were stationed at Fort Pickens near Pensacola.