She made her acting debut in 2016, since then, she has appeared in number of films and television series.

[2][3] Choi Myung-bin is affiliated to artist management company Prain TPC.

[4] In 2021 Choi played young female protagonist in KBS historical romance drama The King's Affection and was praised for her dual performance as Crown Prince Lee Hwi and court maid Dam-yi.

[5] The same year, she was cast in KBS2 weekend drama Young Lady and Gentleman as Lee Jae-ni - eldest daughter of male lead.

[7] In 2022 she appeared in tvN coming-of-age romantic drama Twenty-Five Twenty-One as Kim Min-chae, the daughter of protagonist.