It is located on the tidal Choptank River, which flows into Chesapeake Bay.

Tradition has it that the name "choptank" was a crude Anglicisation of the Algonquian name for the river, probably in the Nanticoke language.

[5] The town is located at the southwestern corner of Caroline County on the northeast bank of the Choptank River, just north of where Hunting Creek enters the river from the east.

Choptank Road leads northeast 3 miles (5 km) to the town of Preston and the nearest state highways, Maryland Routes 16 and 331.

This article about a location in Caroline County, Maryland is a stub.