He also worked briefly for TVG Network, a horse racing channel, and was the host of Designers' Challenge on HGTV.

His co-hosts were Dancing with the Stars judge Carrie Ann Inaba, and Pussycat Dolls member Nicole Scherzinger.

In April 2015, Disney-ABC announced that Harrison would replace Terry Crews as host of the syndicated version of Who Wants to Be a Millionaire?

[8] GSN began airing reruns of this show on December 18, 2017, marking a return to the network for him since the cancellation of Mall Masters.

Harrison earned two nominations for Outstanding Game Show Host in 2018 and 2019, but lost to Wayne Brady and Alex Trebek, respectively.

[11] On February 13, 2021, Harrison announced that he would be temporarily stepping aside from the franchise after facing criticism for defending a contestant on The Bachelor accused of racism.