[2] Discovered in 2003 after going through his first major audition, Lowell landed the role of Jonathan Fields on the ABC teen drama Life As We Know It.

After the end of Life As We Know It, Lowell was cast as Stosh "Piz" Piznarski in the third season of Veronica Mars, opposite Kristen Bell and Jason Dohring.

From 2007 until 2010, Lowell appeared in the ABC drama Private Practice, alongside Kate Walsh, Audra McDonald, and Tim Daly, playing Dell, the receptionist for the Oceanside Wellness Group who was also a qualified nurse, midwife-in-training, and young father to six-year-old daughter Betsy.

Lowell exited Private Practice in the show's third-season finale when Dell died from heart failure, a complication during brain surgery after a vehicle accident.

[4] Set in Michigan’s Upper Peninsula, the film tells the story of a man redefining his outlook on life after the death of his parents.