The Protestant faith came with British traders and American missionaries who reached Bangkok in the early years of the 19th century, but made little progress until the country opened to the West during the enlightened reign of King Mongkut Rama IV (1851-1868).

At first, Bangkok's Protestants met for worship in each other's homes, but as their numbers increased they felt the need for a church building of their own.

To a petition's response, King Mongkut granted land near the Chao Praya River for the use of the "community of foreigners who are of Protestant Christian faith," and the newly built church was opened for worship on 1 May 1864.

By the end of the century the congregation had grown, and access by land had become difficult, so it became necessary to build a larger church in a more central location.

On 7 April 1904, His Majesty King Chulalongkorn Rama V graciously granted a larger plot of land at the junction of Convent and Sathorn Roads for the use of the church.

The church is built on a foundation of teak logs, and the walls and pillars are made of brick covered with plaster.

A teak screen, which originally separated the chancel from the nave, is now at the west end of the main body of the church.

It was originally installed back to front, but was re-installed correctly as part of a restoration of windows, which took place in 2012.